Periodontal Pocket Depth in Relation to Salivary Osteonectin among Osteoporotic Old Adult Women

Abstract

Osteoporosis is a systemic skeletal disorder characterized by compromised bone strength The association between systemic osteoporosis and periodontal health remains controversial many studies found a relationship between clinical measures of periodontal disease and salivary levels of osteonectin asit is essential for normal bone mass. This study was conducted to measure salivary osteonectin in relation to periodontal pocket depth among osteoporotic women and compared to control group.Materials and Methods: 60 females aged 60-65 years attending Al-Yarmook Teaching Hospital were included in the present study , The 30 patients diagnosed with osteoporosis by measuring bone density at the spine and femur with a dual-energy X-ray absorptiometry at T-score of >2.5, and 30 women without osteoporosis with T-score of<-1 (control group). The periodontal health condition was assessed using periodontal pocket depth . Stimulated salivary samples were collected under standardized condition, according to the criteria of Tenovuo and Lagerlöf, (1994). The saliva was analyzed for estimation of glycoprotein (osteonectin) by using Enzyme-linked immunosorbent assay (ELISA).Results: The data of the present study illustrates that the mean rank value of probing pocket depth (PPD) was found to be higher among control group than osteoporotic women but the difference was not significant in addition the mean rank value of both ≥4 and ≥5 thresholds of PPD was found to be higher among osteoporotic women than control groups, while opposite figure was found concerning PPD ≥3, however all these differences were statistically not significant. Analysis among osteoporotic group revealed that the salivary osteonectin correlate very weakly not significantly in positive direction with all threshold Conclusions: The Osteoporosis associated with decreased bone mineral density had an effect on oral health status, leading to an increase in periodontal disease. This was slightly affected by changes in salivary osteonectin. Therefore old adult women may need special oral health preventive and educational programs.